Background Hypnic jerks are generally viewed as benign, transient motor events at sleep onset. In rare cases, however, they evolve into...

Goals of Research Team Define what (excessive fragmentary) hypnic jerking is by developing and testing SOVM  (Sleep-onset...

Voltage Gated Ion Channels and Sleep. The Journal of Membrane Biology  (Volume 257, Issues 5–6, Pages 269–280) published December 2024,...

09/20/2025 Next-Gen Disease Screen (NGDS) & Related Tools Next-Gen Disease Screen (NGDS) • NGDS screens hundreds of genetic markers for...

Article Integration Summary – SOVM Sleep-Onset Oscillatory Vasomotor Myoclonus 1. RAAS in PTSD: ACE and ARBs Reduce Symptoms (J Clin...

SOVM Sensitivity & Variability The following summarizes the integrated framework linking the three main sensitivity categories observed...

Propriospinal Myoclonus: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736211/ Surgical Treatment of Propriospinal Myoclonus: [...

Angiotensin is a protein hormone that causes blood vessels to become narrow. It helps us to maintain blood pressure and fluid balance in...

Dear CoRDS Partners, We hope you all are doing well and your new year is off to a great start. As you have noticed, CoRDS has been...

Genetics, informing use of Diamox: In this article on central nervous system channelopathies, the below figure and table lists the...

In the article "Twinkling, star-shaped brain cells may hold the key to why, how we sleep". It's amazing how little we know about sleep....

Hypnic Jerking has had many names and has been hard to detect on testing. The diagnosis is easily overlooked because the involved muscle...