SOVM Sensitivity & Variability The following summarizes the integrated framework linking the three main sensitivity categories observed...

Reframing Chronic Hypnic Jerks Through A Neurovascular Lens — Informed by Case Study and Group Trends Disclaimer The attached manuscript has not yet been peer-reviewed. It is intended for early sharing and discussion. For feedback or inquiries, please contact the author at the address below. Posted: [6/23/25], Version: [5.2/final] Review, sharing, and constructive feedback from patients, clinicians, and researchers are encouraged to support the ongoing refinement of thi

Dear CoRDS Partners, We hope you all are doing well and your new year is off to a great start. As you have noticed, CoRDS has been working on new features for participants, partners, and now researchers. We are excited to announce the launch of our new researcher access portal. This portal will be used for researchers to submit requests for data or to have CoRDS contact participants on their behalf. Researchers will be able to obtain the de-identified data in real time throug

Genetics, informing use of Diamox: In this article on central nervous system channelopathies, the below figure and table lists the genetic mutations along with the corresponding body systems and medications that treat them. Several people in the hypnic jerking group have received epilepsy genetic panel screens (you do not need to be having “seizures” to have an epilepsy genetic panel run). The identified mutations of group members indicate that Diamox could be an appropriate

In the article "Twinkling, star-shaped brain cells may hold the key to why, how we sleep". It's amazing how little we know about sleep. Transitioning to sleep involves cellular calcium signaling. “The findings of this study suggest that we may have been looking in the wrong place for more than 100 years," said senior author and professor of biomedical sciences Marcos Frank. "It provides strong evidence that we should be targeting astrocytes to understand why and how we sleep,

Below are highlights of what has worked with people from our Facebook community threads. It is not meant to be medical advice and should be reviewed by your medical practitioner. We have many similar patterns. However, each case seems to be slightly different. Information below is culled from close to two decades of data gathering. Its biggest influence, however, has been the data from trials involving our Facebook group over the last three years. Most of it can be summarized