Background Hypnic jerks are generally viewed as benign, transient motor events at sleep onset. In rare cases, however, they evolve into...

Goals of Research Team Define what (excessive fragmentary) hypnic jerking is by developing and testing SOVM  (Sleep-onset...

Voltage Gated Ion Channels and Sleep. The Journal of Membrane Biology  (Volume 257, Issues 5–6, Pages 269–280) published December 2024,...

09/20/2025 Next-Gen Disease Screen (NGDS) & Related Tools Next-Gen Disease Screen (NGDS) • NGDS screens hundreds of genetic markers for...

Article Integration Summary – SOVM Sleep-Onset Oscillatory Vasomotor Myoclonus 1. RAAS in PTSD: ACE and ARBs Reduce Symptoms (J Clin...

SOVM Sensitivity & Variability The following summarizes the integrated framework linking the three main sensitivity categories observed...

Reframing Chronic Hypnic Jerks Through A Neurovascular Lens — Informed by Case Study and Group Trends Disclaimer The attached manuscript has not yet been peer-reviewed.   It is intended for early sharing and discussion. For feedback or inquiries, please contact the author at the address below. Posted:  [6/23/25], Version:  [5.2/final] Review, sharing, and constructive feedback from patients, clinicians, and researchers are encouraged to support the ongoing refinement of thi

Propriospinal Myoclonus: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736211/ Surgical Treatment of Propriospinal Myoclonus: [...

Angiotensin is a protein hormone that causes blood vessels to become narrow. It helps us to maintain blood pressure and fluid balance in...

Dear CoRDS Partners, We hope you all are doing well and your new year is off to a great start. As you have noticed, CoRDS has been working on new features for participants, partners, and now researchers. We are excited to announce the launch of our new researcher access portal. This portal will be used for researchers to submit requests for data or to have CoRDS contact participants on their behalf. Researchers will be able to obtain the de-identified data in real time throug

Genetics, informing use of Diamox: In this article on central nervous system channelopathies, the below figure and table lists the...

In the article "Twinkling, star-shaped brain cells may hold the key to why, how we sleep". It's amazing how little we know about sleep....

Hypnic Jerking has had many names and has been hard to detect on testing. The diagnosis is easily overlooked because the involved muscle...